Hiring company: Lilly
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.
Senior Research Scientist, In Vivo Pharmacology Gene Therapy
About Prevail Therapeutics
Prevail, a wholly owned subsidiary of Eli Lilly and Company, is a biotechnology company focused on developing novel gene therapies for Parkinson’s disease and other genetically defined neurodegenerative diseases. Prevail is based in the Alexandria Centre for life Sciences on the East Side of Manhattan in New York city.
Position Summary
The Senior Research Scientist, In Vivo Pharmacology Gene Therapy, will lead an in vivo pharmacology lab, located in Indianapolis, to support the discovery and optimization of novel therapeutic candidates for Gene Therapy. As part of the Prevail discovery team, s/he will be a key driver to advance novel targets for neurodegenerative disorders, as well as exploring AAV biodistribution and clearance.
Responsibilities
- Establish an in vivo pharmacology lab to design and conduct in vivo pharmacology studies to characterize activity of gene therapy vectors in mouse models
- Lead biologist for gene therapy programs in CNS disorders. Collaborate with the in vitro team of Prevail in NY for vector generation, optimization and characterization.
- Collaborate with cross-functional partners (Preclinical, toxicology, ADME, PK/PD modelling, regulatory, clinical and manufacturing team) to ensure the translation from discovery to development
- Investigate the in vivo distribution and clearance of AAV
- Drive the inception and execution of novel target projects
Basic Qualifications
- MS/PhD in biology or related disciplines. MS with 10 years or PhD with 3-5 years of experience in Gene therapy or Neuroscience is required.
Additional Skills/Preferences
- Passion, knowledge and experience in neuroscience or rare disease research.
- Prior experience in macromolecule distribution and metabolism
- Strong analytic thinking skills. Demonstrated ability to articulate issues, and extract and synthesize complex issues into key focus.
- Creative and curious. Can quickly adapt in a fast-paced working environment
- Strong inter-personal and communication skills. Proven record to collaborate and network across a wide variety of functions and work effectively with internal and external partners.
For internal employees, if you are currently in a technical path role, but outside of the posting band, you may apply. You will be hired at your current level. For example: Current P4 (tech ladder), Posting R1-2 tech ladder, hire will occur at P4
Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
As a condition of employment with Eli Lilly and Company and its subsidiaries in the United States and Puerto Rico, you must be fully COVID-19 vaccinated and provide proof of vaccination satisfactory to the company. If you would like to request an accommodation for medical or religious reasons, you may do so at workplace_adjustment@lilly.com.